October 6 holds significance in Indian history for the birth anniversaries of renowned scientist Meghnad Saha, actor and politician Vinod Khanna, spiritual leader Kripalu Maharaj and several other prominent personalities. The date is also associated with the deaths of important Indian political and cultural figures, including V. K. Krishna Menon and former Maharashtra Chief Minister Babasaheb Bhosale.

October 6 is also observed internationally as World Cerebral Palsy Day, which focuses on awareness, inclusion, accessibility and equal opportunities for people with cerebral palsy. In India, the date also falls during Wildlife Week, observed from October 2 to 8.
One of the notable historical events associated with October 6 is the birth of Meghnad Saha in 1893. The renowned Indian astrophysicist developed the Saha ionisation equation, which became an important tool for understanding stellar spectra and the physical conditions of stars. He also contributed to the development of scientific institutions in India. The India Science, Technology and Innovation portal records October 6, 1893, as his birth date.
In 1949, the foundation stone of the National Defence Academy (NDA) building at Khadakwasla, Pune, was laid by Prime Minister Jawaharlal Nehru, according to historical records.
Another important date in Indian political history is October 6, 1974, when V. K. Krishna Menon, the former Defence Minister, diplomat and nationalist leader, died. He had represented India on the international stage and served as Defence Minister during the early years of the republic.
Several notable Indians were born on October 6 across science, politics, cinema and public life.
| Year | Name | Events |
| 6 October, 1506 | Baba Buddha | Revered Sikh spiritual figure associated with the early Sikh tradition |
| 6 October, 1879 | Hussain Ahmad Madani | Islamic scholar and freedom movement figure |
| 6 October, 1893 | Meghnad Saha | Pioneer of Indian astrophysics and institution builder |
| 6 October, 1922 | Kripalu Maharaj | Spiritual leader and religious teacher |
| 6 October, 1930 | Bhajan Lal | Former Haryana Chief Minister |
| 6 October, 1933 | Mukarram Jah | Former titular Nizam of Hyderabad |
| 6 October, 1944 | Jitan Ram Manjhi | Indian politician and former Bihar Chief Minister |
| 6 October, 1946 | Vinod Khanna | Popular Hindi film actor who later entered politics and served as a Union minister |
| 6 October, 1963 | Sanjay Mishra | Indian actor known for his work in Hindi cinema |
| 6 October, 1982 | Meiyang Chang | Actor, singer and television personality |
| 6 October, 1985 | Sabyasachi Mishra | Odia actor and performer |
| 6 October, 1988 | Dhruva Sarja | Kannada film actor |
October 6 is associated with the birth anniversaries of several Indian political figures. Bhajan Lal, born in 1930, served multiple terms as Haryana Chief Minister. Jitan Ram Manjhi, born in 1944, served as Chief Minister of Bihar. Vinod Khanna, born in 1946, represented Gurdaspur in the Lok Sabha and also served in the Union government. Partha Chatterjee and Talasani Srinivas Yadav are among other political personalities associated with this date.
Indian cricket also has several personalities associated with October 6. Smitha Harikrishna, born in 1973, is an Indian cricketer. Other Indian players and cricket figures listed for the date include Sanjay Raul (1976), Puneet Mehra (1988), Shraddha Chavan (1988), Prashant Kore (1995) and Sanjula Naik (1996).
October 6 has also witnessed memorable cricket events. In 2018, Prithvi Shaw became the youngest batter to score a Test century on debut, while India defeated the West Indies by an innings and 272 runs.
October 6 marks the death anniversaries of several prominent Indians.
Guru Har Rai, the seventh Sikh Guru, died on October 6, 1661. Nana Saheb, an important figure associated with the 1857 uprising, is traditionally recorded as having died on October 6, 1858. V. K. Krishna Menon died in 1974, while Marathi writer and social worker Dattopant Vaman Potdar died in 1979.
Former Maharashtra Chief Minister Babasaheb Bhosale died on October 6, 2007. Television and film actor Arvind Trivedi, widely remembered for portraying Ravana in the television serial Ramayan, died on October 6, 2021.
World Cerebral Palsy Day is observed on October 6 to raise awareness about cerebral palsy and promote inclusion, accessibility, rights and equal participation for people living with the condition. It is one of the major international observances associated with the date.
October 6 also falls within World Space Week, which runs from October 4 to 10 and highlights the contribution of space science and technology to humanity.
In 2026, World Habitat Day falls on October 5 because it is observed on the first Monday of October, rather than October 6. The United Nations has announced "Adequate Housing for All" as the 2026 theme.
October 6 brings together milestones from science, defence, politics, cinema, cricket and social history. The birth anniversary of Meghnad Saha highlights India's contribution to astrophysics, while the careers of Vinod Khanna, Jitan Ram Manjhi and Bhajan Lal reflect the country's political and public life. The date also remembers figures such as V. K. Krishna Menon, Nana Saheb and Babasaheb Bhosale. Together, these events make October 6 a significant date for understanding India's scientific, political, cultural and historical heritage.