Originally, Delhi University Institute of Pharmaceutical Sciences and Research (DIPSAR) was established in 1964 as Department of Pharmacy at Kashmiri Gate Polytechnic in 1964 and it was one of the departments of Directorate of Training and Technical Education.

In 1972, the department was later shifted to Pusa Institute and then in 1979, to campus was shifted to present lush green of 10.5 acres campus at Pushp Vihar, New Delhi.

From College of Pharmacy it was upgraded and now emerged as Delhi Institute of Pharmaceutical Sciences and Research (DIPSAR) vide gazette notification of July 2004, under Department of Training and Technical Education, Govt. NCT of Delhi and affiliated to the University of Delhi.

With the establishment of the First Pharmacy University of India, Delhi Pharmaceutical Science and Research University (DPSR-U) as per the Govt. Legislation enacted on September 11, 2008, the DIPSAR now is the constituent college of the DPSR University.

At present, DIPSAR is affiliated to the Delhi Pharmaceutical Science and Research University (DPSRU), New Delhi and approved All India Council for Technical Education (AICTE), New Delhi and Pharmacy Council for India (PCI), New Delhi.

Presently, the college offers co-educational undergraduate, postgraduate, and doctorate courses etc. in the field of Pharmacy with various specializations for aspiring students.