Icahn School of Medicine at Mount Sinai is offering an online course called "Introduction to Systems Biology". This 10-week-long course will begin from 31st March, 2014. You can earn a verified certificated at the end of the course.
About the course:
This course will introduce the student to contemporary Systems Biology focused on mammalian cells, their constituents and their functions. Biology is moving from molecular to modular. As our knowledge of our genome and gene expression deepens and we develop lists of molecules (proteins, lipids, ions) involved in cellular processes, we need to understand how these molecules interact with each other to form modules that act as discrete functional systems. These systems underlie core subcellular processes such as signal transduction, transcription, motility and electrical excitability. In turn these processes come together to exhibit cellular behaviors such as secretion, proliferation and action potentials. What are the properties of such subcellular and cellular systems? What are the mechanisms by which emergent behaviors of systems arise? What types of experiments inform systems-level thinking? Why do we need computation and simulations to understand these systems?
The course will develop multiple lines of reasoning to answer the questions listed above. Two major reasoning threads are: the design, execution and interpretation of multivariable experiments that produce large data sets; quantitative reasoning, models and simulations. Examples will be discussed to demonstrate "how" cell- level functions arise and "why" mechanistic knowledge allows us to predict cellular behaviors leading to disease states and drug responses.
Ravi Iyengar, Evren Azeloglu, Jens Hansen and Joseph Goldfarb will be the course instructors.
The course will have a workload of 6-8 hours of work / week.
It will be taught in English and the subtitles will be available in English.
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